Is multidrug-resistant tuberculosis (MDR TB) on the rise?
Since 1993, when the TB surveillance system was expanded to include drug-susceptibility results, reported multidrug-resistant (MDR) TB* cases have decreased in the United States. Among all reported TB cases in the United States, the percentage of primary MDR TB cases decreased from 2.5% (407 cases) in 1993 to 1.0% (86 cases) in 2008. Since 1997, the percentage of U.S.-born patients with MDR TB has remained at 1.0% or less. However, of the total number of reported primary MDR TB cases, the proportion occurring in foreign-born persons increased from 25.3% (103 of 407) in 1993, to 76.7% (66 of 86) in 2008. *Primary multidrug-resistant TB (MDR TB) is defined as no previous history of TB disease and is resistant to at least isoniazid and rifampin, the two best first-line TB treatment drugs.