Is Modulation of Shear Stress the Link to Vascular Prevention?
on behalf of Art.Net. From Art.Net. (Arteriogenesis Network), Universitätsmedizin Berlin-Charité, Center for Cardiovascular Research, Department for Internal Medicine, CC 13 Cardiology, Berlin, and University Clinic Freiburg-Cardiology, Freiburg; and the Max Delbrück Center for Molecular Medicine, Department of Angiogenesis and Cardiovascular Pathology, Germany. Correspondence to Universitätsmedizin Berlin-Charité, Center for Cardiovascular Research CCR, CC 13, Hessische Strasse 3-4, 10115 Berlin, Germany. E-mail ivo.buschmann{at}charite.de’ + u + ‘@’ + d + ”//–> See related article, pages 538–545 Key Words: shear stress arteriogenesis collateral arteries cardiovascular prevention Arteries and veins are permanently exposed to hemodynamic forces because of the pulsatile nature of blood pressure and flow. Hence, the endothelium is constantly detecting different biomechanical forces, cyclic stretch and shear stress in particular,1–2 and converts the latter stimuli into intra- and extrac
