Is metronidazole 0.75% gel effective in the treatment of seborrhoeic dermatitis?
Author(s): Ozcan H, Seyhan M, Yologlu S Affiliation(s): Inonu University, Medical Faculty, Department of Dermatology 44280 Malatya, Turkey. hamdi.ozcan@inonu.edu.tr Publication date & source: 2007-07, Eur J Dermatol., 17(4):313-6. Epub 2007 Jun 1. Publication type: Randomized Controlled Trial The study aimed to evaluate the effectiveness of metronidazole 0.75% gel in patients with mild and moderate seborrhoeic dermatitis. Sixty-seven patients with seborrhoeic dermatitis were enrolled. Cases were randomly treated with metronidazole 0.75% gel or placebo for four weeks and were additionally followed up for another four weeks. Patients were evaluated by scoring before the treatment, once a week during the treatment and twice after the cessation of the treatment within a 15-day interval. Furthermore, patient satisfaction and doctor global evaluation were done at the end of the treatment and of the study as well. In the metronidazole group 33 patients (median age: 26, total severity score: 1