Is Metacam safe to use in conjunction with other medicines?
Specific studies looking at the compatibility of Metacam and other drugs have not been conducted. The respective effect of each drug must be considered from a pharmacological point of view. We know that many drugs have been safely used concurrently with Metacam. These may include heartworm preventatives, vaccination regimens, thyroid supplements, many antibiotics, etc. Some other drugs are also highly protein bound and should be monitored closely when used in conjunction with Metacam. Examples include ACE inhibitors and certain medicines for seizure control. However, because of the mechanism of action for Metacam, it is imperative that certain pharmaceuticals never be used at the same time. These include other NSAIDS, (Deramaxx,® Rimadyl,® Etogesic,® Zubrin,™ and others not approved such as aspirin, ibuprofen, etc.), corticosteroids, and other drugs that are either nephrotoxic or hepatotoxic. Nevertheless, regardless of medication that is administered with Metacam, it is important to r
