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Is mechanical pain threshold after transcutaneous electrical nerve stimulation (TENS) increased locally and unilaterally?

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Is mechanical pain threshold after transcutaneous electrical nerve stimulation (TENS) increased locally and unilaterally?

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Background and Purpose. It is not fully understood how transcutaneous electrical nerve stimulation (TENS) intensity affects mechanical pain threshold. Method. Sixty-six healthy volunteers (13 male, 53 female; 132 hands) without prior experience of TENS participated in the study, which comprised a randomized single-blind controlled trial. TENS was administered for 20 minutes through electrodes (25 x 25 mm) placed on the hands and forearms with a fixed frequency of 100 Hz and pulse duration of 150 micros. TENS intensity was randomized and allocated in a concealed manner so that one arm received TENS with stimulation intensity set at participants’ subjective sensory threshold and the other received TENS with stimulation intensity continuously adjusted by physiotherapists to a strong but comfortable non-painful stimulation. Observers were blinded to stimulation intensity levels. Results. Mechanical pain threshold increased significantly, by a mean total of 0.79 kg/cm(2) (95% confidence int

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