Is LI 160 an MAO Inhibitor?
No. Although it was formerly believed that St. John’s wort worked much like an inhibitor of the enzyme monoamine oxidase (MAO), more recent investigations into the mechanism of action of St. John’s wort have revealed that it does not operate like an MAO inhibitor but rather inhibits the re- uptake of the brain’s chemical messengers serotonin, norepmephrine and dopamine at the endings of nerve fibers. Back to Top An Editorial from the Journal Of Geriatric Psychiatry and Neurology, Volume 7, Supplement 1 “As an extra feature this month, readers of the Journal of Geriatric Psychiatry and Neurology are receiving this Supplement that outlines some very exciting reports on a new pharmaceutical agent. Until 3 months ago, I had never heard of hypericum, but in reviewing these papers and other literature, I have been impressed with the potential of this compound as a therapeutic agent in the treatment of mild-to-moderate depressive illnesses, the kind of depressions that predominate in outpatie
