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Is “Leaky Gut” the Gateway to Autoimmune Reactions in the Brain?

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Is “Leaky Gut” the Gateway to Autoimmune Reactions in the Brain?

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With better understanding of the connection between environmental exposures (nutritional, chemical, and toxic) with gene expression, we can potentially douse the flames of the autoimmune inflammatory mechanism in the brain. Current evidence has outlined the primary role that intestinal barrier function plays in the initiation, propagation and continuation of autoimmune diseases. This presentation will outline the mechanisms by which compromise of barrier integrity may occur, allowing environmental exposures to enter the system, and how the immune system reacts to these perceived threats. This presentation will give attendees an understanding and appreciation of intestinal permeability-its frequency, pathophysiology and ramifications in the world of autoimmunity. We also will address a case-management approach to treatment options.

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