Is it through that Malaria vaccine should be taken before traveling to Nicaragua?
Presently there is no vaccine for malaria. You can however take prophylactic to cover yourself, such a Lariam (melfloquine). If mefloquine is recommended it should be started at least one week but preferably two to three weeks before travel to the malarious region. It should then be taken throughout the stay so that if you are bitten by an infected mosquito, there will be medicine in your blood to prevent malaria developing.