Is it safe to mix Nurofen and Sudafed?
Sudafed has numerous interactions with other drugs, but those do not include Nurofen. Since there are several forms of Nurofen (some include pseudoephedrine), we must not exclude the possibility of some interaction. Sudafed also has pseudoephedrine in its structure and there might be augmentation of the effect. So, you are right, she must talk to the doctor.