Is it safe to alternate acetaminophen and ibuprofen?
If you are using the correct dosage of each medicine at the correct times, then it is probably safe in most children, although there is no research to prove that it helps or that it is safe. The problem is that it is easy to get confused and give an extra dose of one or the other medicines. And in some children, especially if they are dehydrated or have other medical problems, giving both medications can cause serious side effects, especially with the kidneys.