Is it safe for someone with PXE to take Salsalate?
Disalcid (salsalate) is a non-steroidal anti-inflammatory drug (NSAID) that does not have an aspirin-like effect on platelets and is somewhat less irritating to the stomach than aspirin, so it is safer than aspirin for someone with PXE. However, as with Celebrex, the risk of GI bleeding is lower but not zero. Nothing is perfectly safe.