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Is it possible to restrain secondary structure in the target sequence?

April 26, 2017possible restrain Secondary sequence structure target

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Is it possible to restrain secondary structure in the target sequence?

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Yes. There are ‘ALPHA’, ‘STRAND’ and ‘SHEET’ restraint types that the model.restraints.make() command can generate. One specifies the segment which is then restrained to the specified secondary structure conformation.