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Is it possible to provide pooled cryopreserved human hepatocytes?

April 26, 2017cryopreserved hepatocytes Human pooled possible

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10 Posted

Is it possible to provide pooled cryopreserved human hepatocytes?

2 Answers

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CelsistemigIntemigVitrotemigTechnologies Baltimore, MD Posted

Yes, it is possible to pool cryopreserved hepatocytes. Celsis In Vitro Technologies offers the patented¹ LiverPool™ cryopreserved human hepatocytes in various donor configurations like 5-, 10-, 20- and 50-donor pooled cryopreserved hepatocytes. All these configurations are readily available for purchase. Custom preparations are also available. The viability is greater than 70% and the cells exhibit both phase I and II enzymes.

For more information on our LiverPool pooled cryopreserved human hepatocytes check our web site for more information.

http://www.celsis.com/ivt/hepatocytes/purpose-pooled-hepatocytes/

¹The process for producing the LiverPool™ pooled human hepatocyte products is covered by one or more U.S. or foreign patents and patent applications, including U.S. Patent No. 7,604,929.

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10 Posted

A. No. The frequency of receipt of fresh tissue and need to cryopreserve hepatocytes immediately after isolation prevents preparation of hepatocyte pools. However, the end user can thaw and pool hepatocytes from several different donors. This approach is most cost effective for applications that require a large number of hepatocytes.