Is it possible to bind either single- or double-stranded DNA to the MaxiSorp surface?
Single-stranded DNA can be adsorbed to MaxiSorp surface using approximately 10 µg ssDNA per ml PBS, pH 8.2. The stability is uncertain. Based on our experience, ssDNA immobilized on the MaxiSorp surface is so loosely bound that it is removed by stringent washing. Double-stranded DNA will not bind to the MaxiSorp surface. DNA, however, can be covalently bound to NucleoLink Strips, Cat. No. 248259.
Single-stranded DNA can be adsorbed to MaxiSorp surface using approximately 10 µg ssDNA per ml PBS, pH 8.2. The stability is uncertain. Based on our experience, ssDNA immobilized on the MaxiSorp surface is so loosely bound that it is removed by stringent washing. Double-stranded DNA will not bind to the MaxiSorp surface. DNA, however, can be covalently bound to NucleoLink Strips.
