Is it OK for me to use ipratropium (Combivent®, Atrovent®) as well as tiotropium (Spiriva®)?
In order for tiotropium to work it has to get to the spot where it can bind, and research has suggested is that if you use a short‐acting anticholinergics like ipratropium, it can preferentially bind and block, preventing the tiotropium to fully function. While there are some safety concerns from potentially combining these agents, there are also concerns about how effective the drug is going to be. The recommendations are not to combine tiotropium and ipratropium. Q: How do you expect prescribing physicians will react to this study’s information if they are the first ones to see it? Will they take their patients off this treatment? A: It is impossible to predict how physicians will react. That is why it is very important to spread all of the information about this study and the pending results of the UPLIFT® study. Q: How is it planned to get the word out to the public that the results of the UPLIFT® study contradict the study published in JAMA? A: COPD is a disease that for a long, l
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