Is it O.K. to use only certain questions or subscales of the FACIT?
In general, yes. Combining available and relevant subscales should be done thoughtfully. Please keep in mind that many disease-specific subscales were developed to add to the FACT-G what was relevant in a particular type of cancer. This may mean that selecting only a disease-specific subscale will result in missing some important things only captured by the FACT-G. Unless relevancy or patient burden is of significant consideration, we recommend that the entire measure be used, with select subscales or combinations of subscales identified and analyzed as the primary or secondary endpoint(s).