Is it O.K. to combine the estrogen and progesterone shots into one syringe?
According to a pharmacist who is the director of a large national pharmacy, it may not be the best idea to mix the two products. The volume of the estrogen preparation is very small and you may have up to a 10% loss with any injection. This could result in a lower amount of estrogen injected than prescribed. However, there is no problem with mixing the preservatives of the two products, as long as you’re injecting them right away.