Is Human Teeth Regeneration a Prospective Clinical Reality or a Fantasy?
The most common teeth pathologies involve lesions on the crown that are caused by caries and/or injuries, pulp inflammation, diseases of the periodontium and teeth loss. Dental surgeons clinically treat these pathologies by substituting the lost physiological tissue/organ with a nonbiological, artificial material. Although usually the outcome is fairly good, pathological repeats are common [85, 86]. Therefore, an ambitious dream of numerous dentists is to be able to substitute the artificial material with a biological, cell-based one that is able to form a genuine replica of the damaged tooth part or the entire lost tooth. Tissue and organ regeneration has become an extensive, multidisciplinary research field with clear purposes and hopeful clinical prospects for a pleiad of human tissues and organs, such as bones, muscles, liver, heart and kidney, among others [87, 88, 89]. There are hopeful clinical prospects because representatives from all animal phyla are endowed with considerable
