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Is human chorionic gonadotropin useful for identifying and treating nonpalpable testis?

April 26, 2017chorionic gonadotropin Human TestIS treating useful

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Is human chorionic gonadotropin useful for identifying and treating nonpalpable testis?

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Bukowski TP; Sedberry S; Richardson B Section of Pediatric Urology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA. PURPOSE: We evaluated the efficacy of human chorionic gonadotropin (HCG) for identifying and treating nonpalpable testis. We then compared the cost-effectiveness of this approach to that of laparoscopy. MATERIALS AND METHODS: We reviewed patient charts during a 15-month period and identified 51 boys (64 testes) who underwent surgery to correct cryptorchidism. There were nonpalpable testes in 17 cases and bilateral cryptorchidism in 2 for a total of 19 impalpable testes. All patients were offered a full course of HCG. Those electing hormonal treatment received intramuscular injection of 2,000 IU/m.2 HCG (maximum 1,500 IU/injection) 3 times weekly for 3 weeks. RESULTS: A full course of HCG was given in 8 patients (10 testes). Of the 10 testes 8 became palpable after HCG treatment, including 1 atrophic nubbin located in the inguinal canal.