Is Hepatitis B Virus Genotype C Independently Associated With Cirrhosis?
Chronic hepatitis B virus (HBV) infection is the most important risk factor of liver cirrhosis in HBV endemic areas. A research group in China performed a large epidemiological study to investigate the association of HBV genotypes with the development of probable cirrhosis in community-based population. They found that HBV genotype C was independently associated with probable cirrhosis in the hepatitis B antigen-negative subjects.