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Is fixation of tissue samples required prior to PATHOS histoprocessing?

April 26, 2017fixation histoprocessing pathos prior samples tissue

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Is fixation of tissue samples required prior to PATHOS histoprocessing?

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Yes, as is the case for conventional histoprocessing. Tissue samples that are not fixed (e.g., with formalin) prior to histoprocessing will exhibit features of alcoholic fixation, due to the ethanol and isopropanol components of the JFC solution. This is similar to the consequences in conventional processing.