Is delivery by cesarean section a risk factor for food allergy?
Eggesb M; Botten G; Stigum H; Nafstad P; Magnus P Norwegian Institute of Public Health, Division of Epidemiology, Oslo, Norway. BACKGROUND: Cesarean delivery might delay the colonization of the newborn intestine. A delayed or aberrant colonization process has been offered as an explanation for the increase in allergic diseases. OBJECTIVE: The aim of this study was to examine whether cesarean delivery and the use of antibiotics were associated with subsequent food allergy. METHODS: In a population-based birth cohort of 2803 children, information regarding mode of delivery, maternal or infant use of antibiotics, and information on potential confounders was obtained prospectively from parental reports and the Norwegian Birth Registry. Parentally perceived reactions to egg, fish, or nuts, as well as objectively confirmed reactions to egg at the age of 2 1/2 years, were chosen as outcomes. RESULTS: Among children whose mothers were allergic, cesarean section was associated with a 7-fold inc
