Is cystic ovarian endometriosis an asymmetric disease?
OBJECTIVE: To investigate whether asymmetry exists in the left- and right-handed distribution of ovarian cystic lesions in a large series of women with endometriosis. DESIGN: Retrospective evaluation of a case series. SETTING: Tertiary care and referral academic centre for the study and treatment of endometriosis. POPULATION: A total of 1054 consecutive women undergoing first-line surgical treatment for endometriosis in an eight-year period. METHODS: Data were collected on indication for the intervention, age at surgery, parity and disease stage as well as side and size of ovarian endometriomas. MAIN OUTCOME MEASURE: Frequency of left- and right-sided ovarian endometriomas. RESULTS: Histologically confirmed endometriotic ovarian cysts were present in 561 women, which were on the left side in 255 instances, on the right in 148, and bilateral in 158. In the patients with unilateral endometriomas, the observed proportion of left cysts (255/403, 63%; 95% confidence interval, 58% to 68%) wa