Is complete tumor removal one of the important tenets of OMS treatment?
Most neuroblastomas associated with OMS are not aggressive, probably due to both host and tumor factors. I imagine that some day we will probably not be removing them. However, the current recommendation is to remove the tumor in the hope of reducing the antigen “burden” on the immune system. Some children improve after surgery; others do not. Tumor removal is seldom an indication to desist in efforts to redirect the immune response. The reason for this is probably memory function of certain T lymphocytes.
