Is chlorine dioxide effective against biofilm?
Chlorine dioxide, like ozone, is a dissolved gas that penetrates biofilm by molecular diffusion. However, unlike ozone, chlorine dioxide is stable and soluble, allowing it to travel to the base of the film where it attacks microorganisms and destroys the biofilm at its point of attachment. Other oxidisers react mostly on the surface of the biofilm to form an oxidised layer, like charring on wood. This precludes further penetration. No other biocide has been shown to control biofilm better than chlorine dioxide.