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Is chemotherapy failure a contraindication for liver resection in liver metastases of colorectal cancer?

April 26, 2017cancer chemotherapy colorectal contraindication failure liver metastases resection

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Is chemotherapy failure a contraindication for liver resection in liver metastases of colorectal cancer?

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Sub-category: Colorectal Cancer (including liver metastases) Category: Gastrointestinal (Colorectal) Cancer Meeting: 2007 ASCO Annual Meeting Session Type and Session Title: General Poster Session, Gastrointestinal (Colorectal) Cancer Abstract No: 4066 Citation: Journal of Clinical Oncology, 2007 ASCO Annual Meeting Proceedings Part I. Vol 25, No. 18S (June 20 Supplement), 2007: 4066 Author(s): U. P. Neumann, A. Thelen, S. Jonas, H. Riess, P. Neuhaus Abstract: Background: Liver resection is the only curative treatment offering a chance of long-term survival in patients with colorectal liver metastases. Chemotherapy is increasingly proposed as neoadjuvant treatment in patients with irresectable liver metastases. However, a large number of patients show progress while on chemotherapy. Recent data indicated that liver resection in patients receiving chemotherapy with tumor progress is associated with poor outcome. The aim of the study was to identify risk factors for poor outcome in patie