Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Is C. DIFF CHEK™ different from toxin ELISAs?

April 26, 2017diff different elisas toxin

0

Posted

Is C. DIFF CHEK™ different from toxin ELISAs?

1 Answer

0

Posted

Yes. C. DIFF CHEK™ is more similar to culture in that it detects the presence of the organism rather than detecting the toxins. The toxin ELISAs detect Toxin A and/or Toxin B of C. difficile. Because about 20% of C. difficile isolates do not express the toxins, and all C. difficile express glutamate dehydrogenase at high levels, you will get samples that are positive in the C. DIFF CHEK™ but negative in ELISAs for the toxins.