Is any new therapy for treatment of chronic GVHD available?
Investigators at Fred Hutchinson have recently opened a new protocol for treatment of newly diagnosed chronic GVHD. This is a multi-center double-blind study involving the addition of mycophenolate mofetil (MMF) or placebo to the standard treatment of prednisone plus cyclosporine or tacrolimus. The objectives of the study are to test the effectiveness of adding MMF and to assess whether the addition of MMF improves quality of life, due to a faster prednisone taper.
