Is Advocate safe for use on pregnant and lactating dogs and cats?
Imidacloprid and moxidectin, the active ingredients in Advocate, have been extensively studied individually and both ingredients have been shown to be non-carcinogenic, non-mutagenic and non-teratogenic (not causing birth defects). Both active ingredients have individually shown no problems with use during pregnancy. Reproductive safety studies with Advocate have not been completed at this time.