Is adiposity across life associated with subsequent hysterectomy risk?
OBJECTIVE: To examine the associations between adiposity at time points from early life onwards and subsequent hysterectomy risk. DESIGN: Prospective birth cohort study. SETTING: England, Scotland and Wales. POPULATION: Women from the Medical Research Council National Survey of Health and Development study, with complete data on hysterectomy status (n= 1790). METHODS: Survival analysis methods were used to examine the associations between body mass index at time points across life and subsequent hysterectomy rates. MAIN OUTCOME MEASURE: Self-reported hysterectomy with or without oophorectomy. RESULTS: From 20 years onwards, those women who were classified as underweight had lower hysterectomy rates, and from 36 years onwards, those women who were overweight had higher hysterectomy rates than those who were normal weight. Women who were obese in adolescence and early adulthood had lower rates of hysterectomy than those who were normal weight, although numbers categorised as obese at the
