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Is additional research planned to follow up on the Breast Cancer and the Environment on Long Island Study?

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Is additional research planned to follow up on the Breast Cancer and the Environment on Long Island Study?

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There are many studies under way that are using the population, data, or specimens from the Breast Cancer and the Environment on Long Island Study. Dr. Gammon and colleagues are continuing to follow the women who participated in the study to determine whether organochlorine compounds (including DDT/DDE, PCBs), PAH, and lifestyle factors influence survival of Long Island women diagnosed with breast cancer. This study is funded by NCI. &#149Dr. Gammon is also examining p53 protein in tumor tissue. P53 is a gene which normally regulates the cell cycle and protects the cell from damage to its genome. Mutations, or changes, in this gene cause cells to develop cancerous abnormalities. This p53 study is funded by the U.S. Department of Defense (DOD). &#149Habibul Ahsan, M.D., of Columbia University, New York, and colleagues are examining whether certain common variations in the sequence of DNA involved in the biosynthesis and metabolism of estrogen and environmental carcinogens are associated

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