Institutional Animal Care and Use Committee (IACUC) Acquiring Approval and Other Frequently Asked Questions How does an investigator acquire approval for a research protocol involving animals?
• The Principal Investigator (PI) for the research project completes and submits an IACUC Protocol form by e-mail. • All project personnel must complete the following RPI Training modules prior to approval of any protocol • Animal Research Overview • Lab Safety Training • Blood-Borne Pathogen • The IACUC will review the protocol submission at a regularly scheduled meeting or via an expedited review process and notify the PI of its decision in writing. • Institutional Biosafety Committee (IBC) approval must be acquired prior to IACUC action for all projects that involve the use of recombinant DNA, recombinant RNA, viruses, viral vectors, toxins, human cells or bacteria. • Institutional Stem Cell Research Oversight (ISCRO) Committee approval must be acquired prior to IACUC action for all projects that involve the use of human stem cells in animal research (for example, the creation of chimeras). • Once approved, the IACUC protocol must be signed by all project personnel, including the PI
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