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In what situations does a researcher need to contact the IRB after research has been approved?

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In what situations does a researcher need to contact the IRB after research has been approved?

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If the researcher wants to make any significant changes in the research or encounters any unanticipated problems involving risk to participants or others, the CPHS must be contacted. See Requests for Modification and Unanticipated Risks on page 11 and page 10 of Policies and Procedures.

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