In the event that persons are exposed to potentially aerosolized Bacillus anthracis spores, what will CDC recommend to prevent inhalation anthrax?
CDC will recommend 60 days of selected oral antibiotics in conjunction with a 3-dose regimen (0, 2 weeks, 4 weeks) of anthrax vaccine (BioThraxT, formerly known as AVA) as an emergency public health intervention. Two major U.S. national advisory bodies have considered strategies for post-exposure prophylaxis for prevention of inhalation anthrax among individuals exposed to potentially aerosolized B. anthracis spores. Both groups, the Advisory Committee on Immunization Practices (ACIP) and the John Hopkins Working Group on Civilian Biodefense, concluded that based on available data, the best means for prevention of inhalation anthrax is prolonged antibiotic therapy in conjunction with anthrax vaccination. In addition, a recent Institute of Medicine Report on anthrax vaccine safety and efficacy also concluded that based on limited animal studies, anthrax vaccine administered in combination with antibiotics following exposure to B. anthracis spores may help to prevent the development of i
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