In practical terms, once a woman has a positive screen result, should she be counselled as per the risk estimate on the report?
Yes. The risk estimate provided on her report is the best estimate of her risk for having an affected pregnancy based on the combination of her age, the results of her blood test(s) and, if available, the nuchal translucency measurement. The patients calculated risk as indicated on her report should be used in the counselling. For example, the 32 year old woman who had SIPS and screens positive with a risk of Down syndrome of 1 in 240 should be counselled that the best estimate of her risk is 1 in 240. This means that for 240 women with this same risk, one will have an affected baby and 239 will not.