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In plaque psoriasis, what is the dosage of ENBREL and how is it administered?

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In plaque psoriasis, what is the dosage of ENBREL and how is it administered?

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For moderate to severe plaque psoriasis, the recommended starting dose of ENBREL for adult patients is 50 mg, twice a week (3 or 4 days apart), given for 3 months. After 3 months, the recommended dose is to step down to 50 mg once weekly. Step-down dosing that is easy to learn: • Step 1: ENBREL 50 mg twice weekly for the first 3 months • Step 2: ENBREL 50 mg once weekly for maintenance after 3 months A 50-mg dose can be given as one subcutaneous (SC) injection using the Enbrel® (etanercept) SureClick® autoinjector or the 50 mg/mL single-use prefilled syringe. 25 mg/0.5 mL prefilled syringes and 25 mg vials of ENBREL are also available.

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