In JIA, what is the dosage of ENBREL and how is it administered?
The recommended dose for pediatric patients ages 2 to 17 years with active polyarticular JIA is 0.8 mg/kg per week (up to a maximum of 50 mg per week). For pediatric patients weighing 63 kg (138 pounds) or more, the weekly dose of 50 mg may be administered using ENBRELĀ® SureClick autoinjectors or prefilled syringes. For pediatric patients weighing 31 to 62 kg (68 to 136 pounds), the total weekly dose should be administered as two subcutaneous (SC) injections, either on the same day or 3 or 4 days apart, using the 25 mg/0.5 mL pre-filled syringe or multiple-use vial. The dose for pediatric patients weighing less than 31 kg (68 pounds) should be administered as a single SC injection once weekly using the correct volume from the multiple-use vial.