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In general, what methods are used to detect EtG? What method does RTL use?

April 26, 2017detect etg method methods RTL Used

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In general, what methods are used to detect EtG? What method does RTL use?

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Methods to detect EtG/EtS include immunoassay (EIA or ELISA), gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS), and liquid chromatography/mass spectrometry/mass spectrometry (LC/MS/MS). Immunoassay methods are of limited specificity and sensitivity with a limit of detection of approximately 1000 ng/mL. GC/MS and LC/MS methods are much more specific than immunoassay, and offer detection limits of approximately 500 ng/mL. LC/MS/MS methods utilize the most technologically advanced instrumentation currently available in forensic and clinical toxicology and provide the highest sensitivity. Redwood utilizes an LC/MS/MS instrument for the confirmation of EtG, which has a limit of detection below 100 ng/mL for each compound.