In addition to scientific merit and the availability of funds, the award criteria in the RFA include programmatic priorities. What does this mean?
A. It means that NIH staff will consider overall program goals in making funding decisions. For the large-scale centers, foremost among the program goals is target selection for structural coverage of sequenced genes and thus the inclusion of wide-ranging groups of proteins. As an example, the NIH staff might decide to fund an application focused on eukaryotes with a high, but not the best, priority score, if all of the top-scoring applications were focused on prokaryotes. For the specialized centers, a crucial goal is the methodology and technology development for each of the three named classes of challenging proteins and other classes of proteins for which the applicants have offered compelling justification. Similar to the previous example, an application focused on membrane proteins might be funded if it had a high, but not the best priority score and was the best application focusing on this class of proteins. Another factor in funding decisions might relate to regional distribut
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