Im using the porphyrin template provided with ConQuest as part of my substructure but the search seems to be missing hits I know are there: what is going on?
Although the templates provided within ConQuest are intended to represent 2D substructures as stored in the CSD, porphyrin is unfortunately a special case as it is difficult to represent all the resonance forms with a single template. Using the template as given in ConQuest will retrieve the majority of porphyrin hits however it may miss cases where some of the bonds are aromatic.