I’m not just interested in depleting serum of abundant proteins, but also in what physiologically binds to serum albumin. Is Seppro® good for this application?
The serum protein complex bound to an anti-HSA IgY is even cleaner than to an anti-HSA monoclonal IgG column. This must be due to less background binding to the Fc portion of IgY compared to IgG, enabling effective Albuminomics™. Virtually every lab that has tested Sigma’s anti-HSA IgY has been very impressed with its exquisite specificity.
