If tyrosinemia 1 is not treated, what problems occur?
The symptoms can vary a great deal from person to person. There are two types of tyrosinemia 1. The more common form happens in infants. The less common form is seen in older children and adults. Tyrosinemia 1 in infants: Babies usually show effects of the condition within the first few months of life. Some of the first symptoms may be: • diarrhea and bloody stools • vomiting • poor weight gain • extreme sleepiness • irritability • “cabbage-like” odor to the skin or urine Liver problems are common. They can lead to: • enlarged liver • yellowing of the skin • tendency to bleed and bruise easily • swelling of the legs and abdomen Kidney problems also happen and can lead to: • rickets, a bone thinning condition • delays in walking Without prompt and careful treatment, babies with severe liver and kidney problems usually die. Some babies also have episodes that include: • pain or weakness, especially in the legs • breathing problems • rapid heartbeat • seizures • coma, sometimes leading to
