If the woman is beyond 12 weeks LMP, can misoprostol be used?
The guidance in this booklet for misoprostol use in incomplete abortion applies when the uterine size is not larger than expected in a 12-week pregnancy. The length of amenorrhea may be longer than 12 weeks, however, since some of the contents of the uterus may have already been expelled. Typically, lower doses are needed for efficacy and safety when the uterus is larger.