If serologic antibody levels are below protective levels for measles in an adult, is it recommended that they receive a repeat MMR?
It is unusual, but vaccine failure is possible (approximately 1/10,000) following two appropriately spaced doses of live-measles-containing vaccine. It is also possible that the laboratory test was not sensitive enough to detect the antibody. If this situation occurs, you can administer a 3rd MMR, document the dose and avoid further testing. If you must have documentation of the response after the 3rd dose, test 4 weeks after the 3rd dose when antibody response to the vaccine will be at peak. Vaccine failure to a 3rd dose is also possible, but even more unlikely (approximately 1/1,000,000).
Related Questions
- If an adult health-care worker has a negative measles titer, should she receive one or two doses of MMR and what is the interval between the two doses?
- If an adult healthcare worker has a negative measles titer, should she receive one or two doses of MMR and what is the interval between the two doses?
- If serologic antibody levels are below protective levels for measles in an adult, is it recommended that they receive a repeat MMR?
