If MM patients are in complete remission, how useful is the sFLC result?
FLC results are more useful than existing SPE or IFE because they are more sensitive and, therefore, more likely to detect residual disease. Also, sFLC concentrations are more likely to be elevated than uFLC levels when patients are in remission. Thus, some patients apparently in full remission by existing tests might have abnormal FLC concentrations and their clinical status will need to be revised. Some patients who relapse between monitoring periods may be more easily identified using sFLC assays rather than SPE or IFE.
