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If I take a painkiller for a tooth ache, how does the medicine know that it needs to umb my tooth and not my foot for example?

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If I take a painkiller for a tooth ache, how does the medicine know that it needs to
umb my tooth and not my foot for example?

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It doesn’t need to know where to work, becuase it doesn’t “numb” at all. Pain killers block pain receptors, so it doesn’t matter where the pain was. The brain is kept from knowing about it, basically.

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