If hazardous drugs are non-sterile does the requirement to use an ISO Class 7 ante-area apply?
Hazardous non-sterile drugs used to compound non-sterile dosage forms such as oral capsules or liquids and topical ointments (among others) should also be handled in a manner to prevent contamination of healthcare workers and others. Personnel protective equipment (PPE) such as gloves should be worn when handling hazardous drugs. Compounding hazardous drugs that are in powder form may require the use of a device to control and contain powder that could become airborne; a fume hood or similar device vented to the outside may be satisfactory. An ISO Class 7 ante area is not required for preparing non-sterile compounded preparations.
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