If haptoglobin levels are decreased, when will they return to normal?
It depends on the cause of the decrease. If it is due to acute hemolysis, such as may be seen with a transfusion reaction, then it will return to normal once the donor blood has been cleared from the system. If it is due to chronic hemolysis, then the concentration should return to normal levels if the underlying condition can be resolved. If the underlying condition cannot be resolved or if the decreased concentrations of haptoglobin are due to decreased production (due to liver disease), then levels may continue to be lower than normal.