If a pregnant woman receives HPV vaccine in the first trimester, what effect is there on the fetus?
HPV vaccine has not been causally associated with adverse outcomes of pregnancy or adverse events to the developing fetus. However, data on vaccination during pregnancy are limited and ACIP has adopted a conservative approach to the vaccination of pregnant women. If a woman is found to be pregnant after initiating the vaccination series, completion of the series should be delayed until after the pregnancy. If a dose is administered during pregnancy, there is no indication for intervention. A vaccine in pregnancy registry has been established by the manufacturer, and women vaccinated during pregnancy should be reported to (800) 986-8999. More information on vaccination during pregnancy is available at http://www.merck.com/product/usa/pi_circulars/g/gardasil/gardasil_pi.pdf.