If a client is on prophylactic antiviral therapy should influenza vaccine be given in the absence of influenza symptoms?
Yes, the vaccine will provide season-long protection from influenza infection even after the post-exposure short term risk is over. Antiviral medication will have no effect on inactivated influenza vaccine (TIV). However, live-attenuated influenza vaccine (LAIV) should not be administered until 48 hours after cessation of therapy using antiviral influenza drugs. If feasible, antiviral medication should not be administered for 2 weeks after LAIV administration.
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